PAPERS RESULTING FROM MU-UMN PEDIATRICS COLLABORATION

A number of research papers have been generated from all this research and they are enumerated below;

  1. Greene JA, Sam-Agudu N, John CC, Opoka RO, Zimmerman PA, Kazura JW. Toll-like receptor polymorphisms and cerebral malaria: TLR2 Delta22 polymorphism is associated with protection from cerebral malaria in a case control study. Malar J. 2012 Feb 15; 11(1):47. PMCID: pending.
  2. Noland GS, Ayodo G, Abuya JS, Hodges JS, Rolfes MAR, John CC. Decreased prevalence of anemia in highland areas of low malaria transmission after a one-year interruption of transmission. Clinical Infectious Diseases 2012; 54(2):178-84. PMCID: PMC3245725.
  3. Bangirana P, Musisi S, Boivin MJ, Ehnvall A, John CC, Bergemann TL, Allebeck P. Malaria with neurological involvement in Ugandan children: effect on cognitive ability, academic achievement and behaviour. Malaria J 2011 Nov 3; 10:334. PMCID: PMC3225331.
  1. Bangirana P, Allebeck P, Boivin MJ, John CC, Page C, Ehnvall A, Musisi S. Cognition, behaviour and academic skills after cognitive rehabilitation in Ugandan children surviving severe malaria: a randomised trial. BMC Neurology 2011, 11:96. PMCID: PMC3171314.
  2. Hawkes M, Opoka RO, Namosopo S, Miller C, Thorpe KE, Lavery JV, Conroy AL, Liles WC, John CC, Kain KC. Inhaled Nitric Oxide for the Adjunctive Therapy of Severe Malaria: Protocol for a Randomized Controlled Trial. Trials 2011, 12(1):176. PMCID: PMC3151218.
  3. Hawkes M, Opoka RO, Namasopo S, Miller C, Conroy AL, Serghides L, Kim H, Thampi N, Liles WC, John CC, Kain KC. Nitric oxide for the adjunctive treatment of severe malaria: Hypothesis and rationale. Med Hypotheses Trials. 2011 Jul 13; 12:176. PMCID: PMC3162048.
  4. Greenhouse B, Ho B, Hubbard A, Njama-Meya D, Narum DL, Lanar DE, Dutta S, Rosenthal PJ, Dorsey G, John CC. Antibodies to Plasmodium falciparum antigens predict a higher risk of malaria but protection from symptoms once parasitemic. J Infect Dis 2011, 204(1):19-26. PMCID: PMC3105040.
  5. John CC , Kutamba E , Mugarura K , Opoka RO . Adjunctive therapy for cerebral malaria and other severe forms of Plasmodium falciparum malaria. Expert Rev Anti Infect Ther. 2010 Sep; 8(9):997-1008. PMCID: PMC2987235.
  1. Idro R, Marsh K, John CC, Newton CR. Cerebral malaria: mechanisms of brain injury and strategies for improved neurocognitive outcomes. Pediatr Res 2010; 68(4):267-74. PMCID: PMC3056312.
  1. Sam-Agudu NA, Greene JA, Opoka RO, Kazura JW, Boivin MJ, Zimmerman PA, Riedesel MA, Bergemann TL, Schimmenti LA, John CC. TLR9 polymorphisms are associated with altered IFN-Ôò¼Ôöé levels in children with cerebral malaria. Am J Trop Med Hyg 2010; 82(4):548-55. PMCID: PMC2844552.
  2. Bangirana P, Nakasujja N, Giordani B, Opoka RO, John CC, Boivin MJ. Reliability of the Luganda version of the Child Behaviour Checklist in measuring behavioural problems after cerebral malaria. Child Adolesc Psychiatry Ment Health 2009; 3:38. PMCID: PMC2799377
  3. Bangirana P, John CC, Idro R, Opoka RO, Byarugaba J, Jurek AM, Boivin MJ. Socioeconomic predictors of cognition in Ugandan children: implications for community interventions. PLOS One 2009; 4(11):e7898.  PMCID: PMC2774512
  1. Bangirana P, Seggane-Musisi, Allebeck P, Giordani B, John CC, Opoka RO, Byarugaba J, Ehnvall A, Boivin MJ. A preliminary examination of the construct validity of the KABC-II in Ugandan children with a history of cerebral malaria. African Health Sciences 2009;9(3):186-92. PMCID: PMC2887024.
  2. Bangirana P, Giordani B, Page C, John CC, Opoka RO, Boivin MJ. Immediate neuropsychological and behavioral benefits of computerized cognitive rehabilitation in Ugandan pediatric cerebral malaria survivors. J DevBehavPediatr 2009; 30:310 ÔÇô318. PMCID: PMC2747354
  1. Opoka RO, Bangirana P, Boivin MJ, John CC, Byarugaba J. Seizure activity and neurological sequelae in Ugandan children who have survived an episode of cerebral malaria. African Health Sciences, 2009; 9:75-81.  PMCID: PMC2707052
  1. Lovegrove FE, Tangpukdee N, Opoka RO, Lafferty EI, Rajwans N, Hawkes M, Krudsood S, Looareesuwan S, John CC, Liles WC, Kain KC. Serum angiopoietin-1 and -2 levels discriminate cerebral malaria from uncomplicated malaria and predict clinical outcome in African children. PLoS ONE 2009; 4: e4912. PMCID: PMC2657207
  1. John CC, Bangirana P, Byarugaba J, Opoka RO, Idro R, Jurek AM, Wu B, Boivin MJ. Cerebral malaria in children is associated with long-term cognitive impairment. Pediatrics 2008; 122:e92-99. PMCID: PMC2607241
  2. John CC, Park GS, Sam-Agudu N, Opoka RO, Boivin MJ. Elevated serum levels of IL-1ra in children with P. falciparum malaria are associated with increased severity of disease. Cytokine 2008; 41: 204-208. PMCID: PMC2323512
  3. Opoka RO, Xia Z, Bangirana P, John CC. Inpatient mortality in children with clinically diagnosed malaria as compared with microscopically confirmed malaria. Pediatr Infect Dis J 2008; 27:319-324. PMCID: PMC2607243
  1. John CC, Panoskaltsis-Mortari A, Opoka RO, Park GS, Orchard PJ, Jurek AM, Idro R, Byarugaba J, Boivin MJ. Cerebrospinal fluid cytokine levels and cognitive impairment in cerebral malaria. Am J Trop Med Hyg 2008; 78(2):198-205. PMCID: PMC2254318
  2. John CC. Cerebral malaria pathogenesis: what can we learn from microarray analysis? Am J Pathology 2007; 171:1729-32.
  3. Boivin MJ, Bangirana P, Opoka RO, Byarugaba J, Idro R, Jurek AM, John CC. Cognitive impairment following cerebral malaria in children: a prospective study. Pediatrics 2007; 119:e360-366. *Cited by the Faculty of Medicine 1000.
  1. John CC, Opika-Opoka R, Byarugaba J, Idro R, Boivin M. Low RANTES levels are associated with mortality in children with cerebral malaria. J Infect Dis 2006; 194(6):837-45.
  2. Bangirana P, Idro R, John CC, &Boivin MJ (2006). Rehabilitation for cognitive impairments following cerebral malaria in African children: strategies and limitations. Trop Med Int Health, 2006; 11:1341-49.
  1. Idro R, Aloyo J, Mayende L, Bitarakwate E, John CC and Kivumbi GW. Severe malaria in children in areas with low, moderate and high transmission intensity in Uganda. Trop Med Int Health 2006 Jan; 11(1):115-24.
  1. Idro R, Bitarakwate E, Tumwesegire S, John CC. Clinical manifestations of severe malaria in the highlands of southwestern Uganda. Am J Trop Med Hyg 2005; 72:561-67.