ACTIVE MU-UMN PEDIATRIC COLLABORATIVE RESEARCH AND TRAINING GRANTS

R01 NS055349          John, Chandy C (PI), Idro Richard (Co-PI)           04/15/08 - 03/31/13 NIH/NINDS
Pathogenesis of cognitive/neurologic deficits in central nervous malaria
This study seeks to establish the areas, frequency and severity of cognitive and neurologic function affected by cerebral malaria in children of different ages (18 months to 4 years and 5 to 12 years) and to identify the immunological/inflammatory and genetic factors associated with cognitive and neurologic deficits in children with severe malaria.

U01 HD064698         John, Chandy C (PI), Opoka, Robert O (Co-PI)    09/30/09-07/31/13 NIH/NICHD
Acute vs. delayed iron therapy: effect on iron status, anemia and cognition
This study aims to determine if 1-month delayed iron therapy in children with iron deficiency and severe malaria leads to improved iron status, anemia and long-term cognition when compared to immediate iron therapy.

U01 HD064698-02S1 John, Chandy C (PI), Opoka, Richard O (Co-PI) 09/30/09 ÔÇô 07/31/13 NIH/NICHD
Acute vs. delayed iron therapy:  effect on iron status, anemia and cognition
This supplement supports closer follow of iron study patients for clinical malaria episodes, and pilot testing  
of a novel cell-phone and community based follow-up method.

D43 NS078280-01    John, Chandy C (PI), Idro, Richard (Co-PI)          08/01/11-07/31/16 NIH/NINDS/FIC           
Research Training in Infection and Neurodevelopment in Uganda           
This grant will provide doctoral level training for students in neuropsychology, immunology, microbiology, biostatistics, and epidemiology, as well as provide training in mentorship for faculty members at Makerere University.
Role: PI

UHN Award Kain, KC (PI), John Chandy C (Co-PI), Opoka Robert O (Co-PI)
01/01/11-12/31/13            UHN, Toronto
Inhaled nitric oxide for the adjunctive therapy of severe malaria: a randomized controlled trial
This study is a randomized clinical trial comparing inhaled nitric oxide to inhaled air for adjunctive therapy of children with severe malaria.